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Gleam

Automating Data Entry for Clinical Trials

joingleam.com
HQ: San Francisco, CA, USA
1-10
B2B

Company research

Public company, workplace, funding, and market signals

Updated Jul 30, 2026

Overview

Gleam Care, Inc. is a San Francisco-based YC S23 startup building a browser-based, human-in-the-loop data-entry assistant for clinical research sites. Its software copies source data into EDC CRFs faster, with traceability and built-in QC, and sells directly to research sites rather than sponsors.

Primary product

Browser-based clinical research site data-entry assistant that moves source data into EDC CRFs with traceability and QC review

Founded

2023

Headquarters

San Francisco, California, United States

Team size

1-10

Industry

Software Development

Sub-industry

Clinical research site data-entry software

Offices

San Francisco, CA, United States

Business model

B2B software
direct site contracts
browser-based SaaS

Funding

Stage

Pre-Seed

Total raised

$500K

Latest round

Pre-Seed · Apr 2023

Latest amount

$500K

Pre-Seed

Apr 2023 · Focal

$500K

People & investors

Leadership

Oliver Keh

Founder & CEO

Michael Felix

Founding AI Product Engineer

Investors

1984 Ventures
Focal
Hustle Fund
Liquid 2 Ventures
Y Combinator

Work & culture

The company emphasizes a site-first, human-in-the-loop culture: 'felt, not seen', 'verify, then trust', and a product philosophy that explicitly says it optimizes for joy.

Product & market

Pricing

Direct-to-site, request-a-demo sales model; public pricing is not posted.

Differentiators

  • —Works alongside existing browser-based eSource and EDC systems
  • —No complex installation
  • —Zero integrations needed
  • —Human-in-the-loop review before submission
  • —Traceability back to source data
  • —Built for clinical research sites rather than sponsors
  • —Fetch-Fill-Trace workflow
  • —Paper/PDF support is planned

Technology

React
GraphQL
RDS
Impact

Customers

Hightower Clinical
Yuma Clinical Trials
CNS Healthcare

Competitors

CRIO
Florence Healthcare
Medidata Rave EDC
Veeva Vault EDC
Castor
Medrio
OpenClinica

Scale & contact

Estimated monthly visits

324

Traffic estimate as of Nov 2024

support@joingleam.com

Latest news

Why the FDA and Sponsors Support Research Sites Using AI

Gleam blog · Jun 2026

Explains Gleam's position on AI-assisted data entry for research sites, arguing that human-reviewed, traceable AI does not change site accountability and is compatible with FDA expectations when the system is fit for purpose and users remain responsible.

Note to File: Oliver Keh

Gleam blog · Jun 2026

Podcast-style article featuring Oliver Keh discussing AI at research sites, FDA perceptions, eSource, and the persistent pain of manual data entry.

Optimizing for Joy

Gleam blog · Apr 2026

Michael Felix discusses Gleam's culture and product philosophy, including 'optimizing for joy', 'felt, not seen', and 'verify, then trust'.

Trust Is Built Field by Field

Gleam blog · Mar 2026

Sets out Gleam's trust and transparency principles for clinical research data entry, emphasizing human-in-the-loop review and source traceability.

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