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Zenflow

Zenflow logo

Zenflow

Medical device that provides a more effective, less invasive…

zenflow.com
HQ: South San Francisco, CA, USA
11-50
Healthcare

Company research

Public company, workplace, funding, and market signals

Updated Jul 30, 2026

Overview

Zenflow is a South San Francisco medtech company developing and commercializing the Zenflow Spring system for benign prostatic hyperplasia (BPH), a minimally invasive, reversible treatment designed for office-based urology care.

Primary product

Zenflow Spring Implant and Delivery System (Spring)

Founded

2014

Headquarters

South San Francisco, California, United States

Team size

20-30

Industry

Medical Equipment Manufacturing

Sub-industry

Urology / BPH medical devices

Offices

South San Francisco, California, United States

Business model

medical device sale
procedure-enabling hardware
B2B clinical commercialization

Funding

Stage

Series C

Total raised

$80.2M

Latest round

Series C · Nov 2024

Latest amount

$24M

Series C

Nov 2024 · Cook Medical

$24M

Series B

Jun 2021 · Invus Opportunities

$24M

Grant - III

Sep 2019 · National Institutes of Health

$1.3M

Line of Credit

Nov 2018 · Square 1 Bank

Series A

Feb 2018 · Invus Opportunities

$31.4M

People & investors

Leadership

Shreya Mehta

CEO & Founder

Ronald Jabba

COO

Gene Ramirez

CFO

Sierra Yearsley

SVP Clinical & Regulatory

Jamey Nielsen

VP R&D

Founders

Nick Damiano

Co-founder

Investors

Astia Angels
CloudStone Capital
Cook Medical
F-Prime Capital
Golden Seeds
Invus Opportunities
Medical Technology Venture Partners
National Institutes of Health
National Science Foundation
Rosenman Institute at QB3
Square 1 Bank
StartX
SV Tech Ventures
Y Combinator

Work & culture

Mission-driven, patient-centric, and startup-fast; the public messaging emphasizes clinical rigor, regulatory execution, and improving outcomes for men with BPH.

Compensation

Public job postings for senior roles list base salary bands of roughly $100k-$130k and $130k-$150k, plus equity and comprehensive benefits; broader compensation details are not publicly disclosed.

Benefits

comprehensive benefits
equity

Product & market

Pricing

Not publicly disclosed; appears to be a B2B medical-device/procedural commercialization model tied to clinical use and reimbursement.

Differentiators

  • —reversible/removable treatment
  • —office-based or outpatient procedure
  • —flexible cystoscope delivery
  • —no burning, cutting, piercing, or tissue removal
  • —designed to preserve natural anatomy and sexual function
  • —three implant sizes
  • —largest working channel among single-use flexible cystoscopes (for Spring Scope)

Technology

Zenflow Spring implant
Zenflow Spring Scope
single-use flexible cystoscope
nitinol
superelastic shape-memory material
balloon anchor
HD visualization
SolidWorks
FDA QSR Part 820
ISO 13485
EU MDR

Customers

urologists
urology clinics
office-based procedural practices
ambulatory/outpatient settings
patients with BPH

Competitors

UroLift
Rezum
iTind
TURP

Scale & contact

Estimated revenue

$1M-$10M

Estimated monthly visits

7.6K

Traffic estimate as of Jun 2026

info@zenflow.com(650) 419-7556

Latest news

Zenflow presents BREEZE™ pivotal clinical trial results at AUA annual meeting

Zenflow news page · May 2026

Zenflow highlighted presentation of BREEZE pivotal clinical trial results at AUA 2026.

FDA Approves the Zenflow Spring® Implant and Delivery System for Patients with BPH

GlobeNewswire / Zenflow · Dec 2025

Zenflow announced FDA PMA approval of its Spring Implant and Delivery System for BPH.

Zenflow Receives FDA 510(k) Clearance for First-of-Its-Kind Single-Use Cystoscope

GlobeNewswire / Zenflow · Sep 2025

Zenflow received FDA 510(k) clearance for the Spring Scope & Camera Control Unit, a single-use flexible cystoscope.

Three-Year Data of Zenflow’s Spring System Demonstrate Durability of Clinical Benefits for Patients Suffering from BPH

GlobeNewswire / Zenflow · Apr 2025

Three-year ZEST data showed durable symptom relief, including 74% responder rate at 36 months and preserved sexual function.

Zenflow Announces $24 Million Financing Round to Fund FDA Filing & Commercial Preparation

GlobeNewswire / Zenflow · Nov 2024

Zenflow closed a $24 million Series C financing round led by Cook Medical.

AboutCareersContactFDA PMA P250007LinkedIn companyNewsOfficial websiteSeries A press releaseSeries B press releaseSeries C press release
SourcesOfficial homepageAbout ZenflowContact ZenflowZenflow newsZenflow careersSenior Quality Engineer jobSenior R&D Engineer jobFDA PMA P250007Zenflow LinkedIn company pageShreya Mehta LinkedInRonald Jabba LinkedInSierra Yearsley LinkedInJamey Nielsen LinkedIn

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