Drug Development & Delivery · Jun 2025
Industry coverage of the Symeres collaboration and the claimed reaction-yield improvement.
Company research
Public company, workplace, funding, and market signals
Overview
Yoneda Labs is a San Francisco-based biotechnology research startup building AI-driven software to optimize organic chemical reactions and chemical manufacturing. Its main product helps chemists predict reaction conditions, optimize processes, and analyze LCMS data faster than manual or trial-and-error workflows.
Primary product
AI-driven software for chemical reaction optimization (Yoneda Optimize / Yoneda Predict / Yoneda Analyze)
Founded
2023
Headquarters
San Francisco, California, United States
Team size
1-10 employees
Work style
Onsite
Industry
Biotechnology Research
Sub-industry
AI software for chemical reaction optimization / computational chemistry
Offices
San Francisco, California, United States
United Kingdom
United States
Business model
B2B software
Enterprise SaaS
Early-access / demo-led sales
Lab-enabled data generation services
Funding
Stage
Seed
Total raised
$4.1M
Latest round
Seed · Apr 2024
Latest amount
$4M
People & investors
Leadership
Founder, CEO
Founder, Chief Scientist
Founder, CTO
Scott E. Denmark
Advisor
Work & culture
Early-stage, fast-paced startup with a small team and minimal internal structure; employees are expected to work autonomously and help shape the company’s direction.
Work style
Onsite
Compensation
Career postings describe competitive salary and equity; one YC role listed $80K-$140K plus 0.80%-1.50% equity.
Benefits
Competitive salary
Equity
Comprehensive health benefits
Product & market
Pricing
Not publicly disclosed; early-access / demo-based sales with customized enterprise pricing likely.
Differentiators
- —Uses experimentally generated wet-lab data to train models
- —Runs hundreds of reactions weekly to build training sets
- —Predicts reaction conditions without wet-lab experimentation
- —Desktop software can run offline on a chemist’s PC to protect proprietary data
- —Benchmarked as 3x faster than manual methods
- —Case study claims yield improvement from ~30% to >90% with Symeres
Technology
AI/ML models
Bayesian optimization
Lab automation
Robotics / liquid handlers (Opentrons OT-2)
Python
HPLC-MS
LCMS
NMR
Semi-automatic peak processing pipeline
Mocca2 open-source chromatogram processing
Chemical descriptors
Customers
Pharmaceutical companies
Chemical CROs
Process chemistry teams
Drug discovery teams
Chemists working in reaction optimization
Competitors
Reaxys
SciFinder
Traditional one-factor-at-a-time workflows
Design of Experiments (DoE) tools
Other computational chemistry / reaction optimization software vendors
Scale & contact
Latest news
Yoneda Labs · May 2025
Yoneda Labs reported that its collaboration with Symeres improved cross-coupling reaction yields from about 30% to over 90% using AI-driven optimization.
C&EN · May 2024
C&EN reported on Yoneda Labs' $4 million seed round and its AI software for optimizing chemical reactions.
Business Wire · Apr 2024
Official press release announcing the $4 million seed round from Khosla Ventures, 500 Emerging Europe, 468 Capital, Fellows Fund, and Y Combinator.
VentureBeat · Apr 2024
VentureBeat covered Yoneda Labs' $4 million seed round led by Khosla Ventures and its plan to build a foundation model for chemistry.
Jobs and careers at Yoneda Labs
0 jobs at Yoneda Labs
No open positions
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