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Simplex

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Simplex

Production-grade web agents.

simplex.sh
HQ: San Francisco, CA, USA
1-10
B2B

Company research

Public company, workplace, funding, and market signals

Updated Jul 30, 2026

Overview

Simplex Labs, Inc. is a San Francisco-based, YC-backed healthtech automation company building a production-grade web agent API for provider enrollment and other repeatable payer-portal workflows. It emphasizes deterministic, production-ready browser automation with logs/video evidence, security/compliance readiness, and white-glove integration into customers’ existing systems.

Primary product

A production-grade web agent API for provider enrollment and payer-portal automation.

Founded

2024

Headquarters

30 Otis St, San Francisco, CA 94103 Apt 305, United States

Team size

1-10 employees

Industry

Software Development

Sub-industry

Healthcare automation / payer-portal automation / web agent infrastructure

Offices

San Francisco, California, United States

Business model

API
usage-based per-enrollment

Funding

Stage

Pre-Seed

Total raised

$500K

Latest round

Pre-Seed · Sep 2024

Latest amount

$500K

Pre-Seed

Sep 2024 · Y Combinator

$500K

People & investors

Leadership

Shreya Karpoor

Co-founder and CEO

Marco Nocito

Co-founder and CTO

Investors

iAngels
Orange Collective
SBXi
Sterling Road
Y Combinator

Work & culture

Developer-first, reliability-focused, and security-conscious; the company emphasizes deterministic workflows, observability (step logs and video), and hands-on integration with customer systems.

Product & market

Pricing

Flat rate per finished enrollment (effective date or documented denial), with no per-seat, per-credit, or per-attempt fees; month-to-month with no minimums.

Differentiators

  • —End-to-end provider enrollment from CAQH setup through payer final determination
  • —Evidence packets with step logs and video for every enrollment
  • —White-glove integration with Airtable, spreadsheets, Verifiable, and internal systems
  • —Handles 2FA, CAPTCHAs, and broken legacy portal flows
  • —Deterministic production workflows generated from code rather than opaque autonomous behavior
  • —Security/compliance posture highlighted as SOC 2 Type II and HIPAA with BAA/NDA
  • —Per-enrollment pricing aligned to finished outcomes rather than seats or attempts

Technology

Python
TypeScript
REST API
OpenAPI
Python SDK
TypeScript SDK
Webhooks
HMAC-SHA256 webhook signing
Supabase
PropelAuth
browser automation
session replay / video logs

Customers

Telehealth clinics
Healthtech teams
Credentialing teams
Teams automating provider enrollment
Teams using Airtable, spreadsheets, Verifiable, or internal CRMs

Competitors

Browser Use
Dopt
Mewayz

Scale & contact

Estimated revenue

Modeled estimate: about $111.2M annual revenue (range $60.2M-$165.1M, 65% confidence).

Estimated monthly visits

1.4K

Traffic estimate as of Jun 2026

support@simplex.sh+1 646-477-2558

Latest news

Today, we’re launching the Simplex Prior Auth API.

LinkedIn · Apr 2026

Introduces a Prior Auth API for submitting prior authorizations, checking status, searching ICD/drug codes, and retrieving payer-specific form questions.

The hardest part of automating healthcare web portals isn't the browser.

LinkedIn · Feb 2026

Highlights that the difficult part of healthcare portal automation is the messy middle: unstructured data, changing form permutations, and reliable production handling.

Python SDK & Webhook Security

Simplex changelog · Oct 2025

Product update announcing a Python SDK and webhook security enhancements, including request signing.

How we built reliable web agents using context engineering

Simplex blog · Jul 2025

Explains Simplex’s approach to context engineering, including multi-agent context compression and claims of running workflows for 2+ hours without failure.

Simplex debuts developer-first platform for AI agent web automation

American Bazaar Online · Jun 2025

External coverage of Simplex’s launch from stealth as a developer-first AI web automation platform focused on legacy portal workflows.

BlogChangelogDocsGitHub organizationHomepageLinkedIn companyPrivacy policyResourcesSupportTrust center
SourcesOfficial websiteLinkedIn company pageY Combinator company pageYC launch postPrivacy policySupport pageChangelogDocs llms.txtTrust centerGitHub organizationBlog post on context engineeringResources page

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