University of Wyoming News · Jul 2026
Recent university coverage says Sigma Genetics is a company partner on a project to stabilize RNA-lipid nanoparticles in dry state form for transport and storage.
Sigma Genetics is a biotechnology company that is building…
Company research
Public company, workplace, funding, and market signals
Overview
Sigma Genetics is a Seattle-based biotechnology startup building Magnetoporation/Magnetoporator devices that use external pulsed magnetic fields to deliver DNA, RNA, proteins, and other charged molecules into cells. Public sources describe a very small, research-heavy team focused on translational cell-therapy, blood-product, and biomanufacturing use cases. Current sources show Zachary Rapp as CEO, while older YC/profile sources vary on founder naming, so founder/leadership attribution should be treated carefully.
Primary product
Magnetoporation / Magnetoporator device for intracellular delivery
Founded
2016
Headquarters
Seattle, Washington, United States
Team size
1-10
Industry
Biotechnology
Sub-industry
Gene delivery / cell therapy manufacturing platform
Offices
454 N 34th St, Seattle, Washington 98103-8602, US
Seattle, Washington, United States
Business model
Platform/device development
research collaborations
technology licensing
grant-funded R&D
Funding
Stage
Seed / grant-backed
Total raised
$3.7M
Latest round
Non-equity assistance / incubator-accelerator · Mar 2026
People & investors
Leadership
Co-Founder & CEO
Co-Founder, Board of Directors
Board Member
Director of Operations
Heather Marie Wilson, PhD
Senior Scientist
Amanda Frey, PhD
Scientist
Mei Xu, MD, PhD
Scientific Consultant
James Overaa
Mechatronics Engineer
Dr. Joseph Rappold
Advisor
Work & culture
Small, research-heavy biotech startup focused on translational cell and gene delivery; public sources emphasize magnetic-field-based platform development, academic/defense collaborations, and a tiny team.
Visa sponsorship
Limited
Compensation
Public pay signals are sparse. Salary.com estimates an average annual salary of about $103,972, with a range of $91,599-$117,415, and MyVisaJobs shows a 2024 H-1B proffered salary of $115,297 for a Mechatronics Engineer.
Benefits
401(k)
healthcare
disability insurance
pension
paid time off
Social Security
Product & market
Pricing
Not publicly disclosed; appears to combine platform/device commercialization, research collaborations, and grant-funded R&D, with projected downstream economics cited as about $5,000 per CAR-T dose and about $500 per freeze-dried RBC unit in investor materials.
Differentiators
- —Magnetoporation uses external pulsed magnetic fields for intracellular delivery
- —non-invasive compared with electroporation
- —no arcing
- —scalable and adjustable across cell volumes
- —gentler handling with low cell death
- —can deliver DNA, RNA, proteins, and cryoprotectants
- —applicable to RBCs, cell therapy, vaccines, and biomanufacturing
Technology
Google Workspace
jQuery
Nginx
PHP
Bluehost
WordPress
MySQL
Customers
cell therapy developers
biopharma manufacturers
research institutions
blood product / transfusion R&D programs
Competitors
BTX
Thermo Fisher
Lonza
Miltenyi
MaxCyte
Genedit
CellFE
Portal
LogicBio
Scale & contact
Estimated revenue
<$5M
Estimated monthly visits
1.5K
Traffic estimate as of Jun 2026
Latest news
LinkedIn · Mar 2026
LinkedIn’s company page shows Sigma Genetics as active, founded in 2016, with 5 employees and funding entries for 2017, 2022, and 2026.
Google Patents · Nov 2025
A pending patent application names Sigma Genetics as assignee and lists Christopher James Pihl, Matthew Rein Scholz, and Zachary Rapp as inventors.
Life Science Washington Institute · Mar 2025
The profile states Sigma Genetics is a Seattle-based Delaware C-corp founded in 2016, with $1.89M venture capital and $1.73M non-dilutive grant funding and a 2025 goal of raising a $10M Series A.
SBIR.gov · Jan 2025
USAF awarded Sigma Genetics $64,111 for a project using magnetoporation and trehalose delivery to create functional lyophilized red blood cells.
Jobs and careers at Sigma Genetics
0 jobs at Sigma Genetics
No open positions
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