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Serna Bio

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Serna Bio

Genetic Medicine with Small Molecules

serna.bio
HQ: Ontario, CA, USA; Remote
1-10
Healthcare

Company research

Public company, workplace, funding, and market signals

Updated Jul 29, 2026

Overview

Serna Bio is an AI-driven RNA-targeted drug discovery company building small-molecule translational enhancers and a proprietary platform for identifying druggable RNA structures, designing RNA-focused chemistry, and advancing preclinical programs in hard-to-drug diseases.

Primary product

Serna Bio Discovery Platform for RNA-targeted small-molecule drug discovery

Founded

2021

Headquarters

Widnes, Halton, United Kingdom

Team size

1-10 employees

Industry

Biotechnology Research

Sub-industry

RNA-targeted drug discovery / AI drug discovery

Offices

Widnes, Halton, United Kingdom
San Francisco, California, USA (MBC BioLabs home)
Vancouver, Canada

Business model

B2B research collaborations
Milestone-based partnering and option deals
Platform-enabled drug discovery partnerships

Funding

Stage

seed

Latest round

Seed · Sep 2021

Seed

Sep 2021 · Y Combinator

People & investors

Leadership

Rabia Khan

Founder & CEO

Danny Incarnato

Chief R&D Officer

Tim Allen

Director of ChemAI and Vancouver Site Lead

Harini Srinivasan

Head of Platform Biology

Investors

50Years
Hummingbird Ventures
Y Combinator

Work & culture

Public signals portray a lean, mission-driven biotech culture focused on challenging biology, rapid experimentation, and strong team camaraderie; posts emphasize building at pace, staying frugal, and working toward clinic with a collaborative team.

Compensation

No public salary bands or compensation details were found in the sources reviewed.

Product & market

Pricing

Partnering and collaboration agreements with success-based payments, development/regulatory milestones, and commercial milestones

Differentiators

  • —Targets RNA rather than proteins
  • —Uses proprietary functional RNA-structure data (Orion / RNA atlas)
  • —Generative AI chemistry optimized for RNA binders
  • —End-to-end platform from target identification to chemical optimization
  • —Focuses on translational enhancement / protein upregulation
  • —Built around hard-to-drug targets and non-coding RNA

Technology

RNA structure atlas / functional RNA datasets
Polaris generative AI chemistry platform
Ara in-cell chemi-transcriptomics screening platform
Machine learning
Generative AI
Proprietary RNA-small molecule datasets
Python
GitHub
Google Cloud

Customers

Bayer
Chiesi Group
Other biotech/pharma partners

Competitors

Formation Bio
Cellarity
Arpeggio

Scale & contact

info@serna.bio

Latest news

What if controlling gene expression became a small molecule problem?

Serna Bio LinkedIn · May 2026

Serna Bio highlighted its latest preprint and said its platform can design RNA-modulating small molecules from the ground up, including reported potency and expression improvements in a translational enhancement program.

Generative Chemistry Platform for Small Molecules Targeting RNA: A Case Study for Chemical Optimization

bioRxiv · May 2026

Serna Bio published a preprint describing its GenAI chemistry platform for RNA-targeting small molecules, including benchmark results versus public generative models and experimental validation of designed compounds.

Chiesi Group and Serna Bio announce strategic collaboration to discover and develop RNA-targeted small molecules for respiratory diseases

Chiesi Group · Jul 2025

Serna Bio entered a global discovery collaboration with Chiesi Group to find RNA-targeting small molecules for respiratory disease. The deal uses Serna Bio's proprietary platform, includes success-based and milestone payments, and gives Chiesi an option to acquire resulting assets.

Serna Bio Announces Scientific Advisory Board

PR Newswire / Serna Bio · Jan 2025

The company announced a Scientific Advisory Board and described its platform as a preclinical AI-enabled RNA-targeting small-molecule discovery engine focused on translational enhancement, neuro-metabolism, and obesity.

About Serna BiobioRxiv preprintCareersChiesi collaboration press releaseCompany websiteLinkedIn company pageNews & insights blogPartner with usScientific Advisory Board press releaseX profile
SourcesHomepageAboutPartner with usBlogCareersLinkedIn companyXScientific Advisory Board press releaseChiesi collaboration press releasebioRxiv preprint

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