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Persephone Biosciences

Persephone Biosciences logo

Persephone Biosciences

We are using the gut microbiome to end cancer.

persephonebiosciences.com
HQ: San Diego, CA, USA
1-10
Healthcare

Company research

Public company, workplace, funding, and market signals

Overview

Persephone Biosciences is a San Diego-based biotechnology company that combines microbiome research and synthetic biology to commercialize infant/toddler synbiotics and related microbiome-driven health solutions. Its flagship consumer product is the Daily Synergistic Synbiotic (Bloom for infants and Thrive for toddlers), a probiotic-plus-prebiotic powder designed to replenish missing Bifidobacterium and support gut, immune, and developmental health.

Primary product

Daily Synergistic Synbiotic (Bloom for infants 0-12 months; Thrive for toddlers 12-36 months)

Founded

2017

Headquarters

10835 Road to the Cure, Suite 150, San Diego, CA 92121, United States

Team size

11-50

Industry

Biotechnology Research

Sub-industry

Microbiome therapeutics / infant synbiotics

Offices

10835 Road to the Cure, Suite 150, San Diego, CA 92121, United States
3210 Merryfield Row, San Diego, CA 92121, United States

Business model

Direct-to-consumer e-commerce
Subscription commerce
Clinical research and trials
Research partnerships / collaborations

Funding

Stage

seed

Total raised

$15.1M

Latest round

Seed · Jul 2022

Latest amount

$15M

People & investors

Leadership

Stephanie Culler, PhD

CEO & Co-Founder

Steve Van Dien, PhD

CTO & Co-Founder

Richard Insel, MD

Chief Medical Advisor

Veronique Riethuisen

Board Member and CBO

Gillian Snyder

Head of Marketing

Shaun Singer

Director of Poop for the Cure

Bryce Jarman, PhD

Head of Product Development

Pedro Torres, PhD

Head of Computational Biology

Daniel Bradbury

Chairman, Board of Directors

Investors

American Cancer Society’s BrightEdge Fund
Capita3
Fifty Years
First Bight Ventures
Mesa Verde Partners
Ocampo Capital
Pioneer Fund
Propel Bio Partners
Susa Ventures
Y Combinator
ZhenFund

Work & culture

Mission-driven and science-first, with a cross-functional team spanning biotech, clinical development, and direct-to-consumer commercialization. Public copy emphasizes rigorous research, safety testing, and translating microbiome science into consumer health products.

Visa sponsorship

Limited

Compensation

No public salary bands were posted on the careers page. Third-party visa data shows historical H-1B sponsorship and a 2024 average proffered salary around $65K for filed roles, while the company had no open jobs listed on its careers page/Y Combinator listing at the time of review.

Benefits

Free shipping on subscriptions
90-day Peace of Mind return policy
HSA/FSA eligibility via Truemed
Access to a parent community with subscriptions

Product & market

Pricing

Direct-to-consumer retail pricing with one-time purchase and subscription options; Bloom and Thrive were publicly listed at $74.95 one-time or $64.95/month subscription.

Differentiators

  • —Uses Bifidobacterium strains isolated from contemporary infant cohorts
  • —Pairs probiotics with precision-matched human milk oligosaccharide prebiotics
  • —Clinically validated through My Baby Biome and ARTEMIS studies
  • —Clean Label Project First 1,000 Days certified and third-party tested
  • —Age-specific infant and toddler formulations with vitamin D
  • —Science-led DTC brand with educational support and practitioner outreach

Technology

Shopify
Shopify blog / myshopify storefront
Google Analytics
Instagram
LinkedIn
Twitter/X
Customer account portal

Customers

Parents and caregivers of infants (0-12 months)
Parents and caregivers of toddlers (12-36 months)
Pediatric practitioners / clinicians
Research collaborators and healthcare partners

Competitors

Evivo
Lovebug
BioGaia Baby
Culturelle Baby

Scale & contact

Estimated revenue

~$500K-$1M (third-party estimate, 2024)

Estimated monthly visits

6.8K

Traffic estimate as of Oct 2024

help@persephone.bio(858) 682-4777

Latest news

Persephone Biosciences Announces Publication in Cell Host & Microbe Highlighting the Critical Need to Restore Bifidobacterium in the Infant Gut Microbiome

GlobeNewswire · Dec 2025

Reported a publication in Cell Host & Microbe showing modern infant microbiomes are deficient in key Bifidobacterium and highlighting clinical strategies to restore them; the company reiterated its infant synbiotic launch and research framing.

Persephone Biosciences Announces Positive Topline Results from ARTEMIS Clinical Trial of First-of-its-kind Synbiotic for Children

BioSpace · Nov 2025

ARTEMIS topline results reported tolerability, colonization, and improved sleep outcomes in toddlers after 30 days, strengthening the evidence base for the company’s infant/toddler synbiotic.

Persephone Biosciences Announces Topline Results from AMBROSIA Food as Medicine Study with Kroger Health

GlobeNewswire · Nov 2025

Released topline results from the Kroger Health collaboration, showing diet/medical nutrition therapy could improve microbiome composition and move participants between enterotypes.

Persephone Biosciences Unveils First-Of-Its-Kind Synbiotic Designed To Restore Critical Gut Microbes In Babies

GlobeNewswire · Sep 2025

Consumer launch announcement for Bloom/Thrive, including pricing, formulation details, and the company’s explanation that the product is designed to restore missing gut microbes in babies.

Persephone Biosciences set to launch synbiotics for young children

NutraIngredients · Mar 2025

Previewed the company’s upcoming consumer launch and described its age-specific infant and toddler synbiotic strategy, clinical positioning, and differentiators.

AboutCareersFAQsHomepageInstagramLinkedIn companyOur SciencePress & CoverageTeamX / Twitter
SourcesOfficial homepageAbout usTeamCareersOur ScienceBloom product pageThrive product pageFAQsPrivacy policyPress & CoverageLinkedIn company pageSeed financing press releaseARTEMIS topline resultsAMBROSIA topline resultsProduct launch announcement

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