Output Biosciences blog · Nov 2025
Company blog post arguing that drug discovery should move beyond single-target optimization toward system-level, multi-target biology and biologically-aware generative AI.
Teaching Generative AI the Language of Biology
Company research
Public company, workplace, funding, and market signals
Updated Jul 30, 2026
Overview
Output Biosciences is a New York-based biotechnology company building biologically-aware generative AI and large biological models for drug discovery and breakthrough medicines.
Primary product
Biologically-aware generative AI / Large Biological Models for drug discovery
Founded
2021
Headquarters
Union Square, New York, New York 10003, United States
Team size
1-10 employees
Work style
Flexible
Industry
Biotechnology Research
Sub-industry
AI drug discovery / computational biology
Offices
Union Square, New York, New York 10003, United States
Business model
B2B software/platform
drug discovery platform
therapeutics discovery
Funding
Stage
pre-seed
Total raised
$125K
Latest round
Pre-Seed · Aug 2021
Latest amount
$125K
Aug 2021 · Y Combinator
People & investors
Work & culture
Mission-driven and stealth-mode, with messaging that emphasizes repeat founders, biotech veterans, and values of Heart, Excellence, Practicality, Honesty, and Fun.
Work style
Flexible
Visa sponsorship
Limited
Compensation
Public postings describe competitive salary and equity, with medical, dental, and vision coverage.
Benefits
Competitive salary
Equity
Medical coverage
Dental coverage
Vision coverage
Product & market
Differentiators
- —Biologically-aware generative AI
- —Large Biological Models aimed at system-level biology
- —Multi-target drug design focus rather than single-target optimization
- —Team of repeat biotech founders and veterans
Technology
Generative AI
Large Biological Models
Computational biology
Biological reasoning models
Machine learning
Competitors
Arctic Therapeutics
Metagenomi
BioPhy
Scale & contact
Estimated revenue
≈$440K annual revenue (estimated)
Estimated monthly visits
3K
Traffic estimate as of Jun 2026
Latest news
CB Insights · Mar 2024
CB Insights profile describes the company as preventative therapeutics focused on extending human healthspan, and identifies founders, funding, headquarters, and investors.
Built In
Current hiring post describing the company as stealth-mode, backed by Y Combinator, and using a biological reasoning model for AI-driven drug discovery.
Built In
Current hiring post showing the company is still recruiting and describing its preventative therapeutics mission and AI/biotech positioning.
Jobs and careers at Output Biosciences
9 jobs at Output Biosciences
AI Technical Recruiter
Remote
Operations
Remote
2mo ago
Remote
Full-time
Head of Discovery
On-site
Science
New York HQ 🗽
3mo ago
On-site
Full-time
Member of the Technical Staff, Cheminformatics
On-site
Science
New York HQ 🗽
3mo ago
On-site
Full-time
Member of the Technical Staff, Biological Data
On-site
Engineering
New York HQ 🗽
3mo ago
On-site
Full-time
Member of the Technical Staff, Molecular Generation
On-site
Engineering
New York HQ 🗽
3mo ago
On-site
Full-time
Member of the Technical Staff, Pretraining
On-site
Engineering
New York HQ 🗽
3mo ago
On-site
Full-time
Member of the Technical Staff, Interpretability
On-site
Engineering
New York HQ 🗽
3mo ago
On-site
Full-time
Head of Biology
On-site
Science
New York HQ 🗽
3mo ago
On-site
Full-time
Software Engineer, Agents
On-site
Engineering
New York HQ 🗽
3mo ago
On-site
Full-time