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Mindstate Design Labs

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Mindstate Design Labs

Clinical-stage AI neuroengineering platform

mindstate.design
HQ: San Francisco, CA, USA
1-10
Healthcare

Company research

Public company, workplace, funding, and market signals

Updated Jul 29, 2026

Overview

Clinical-stage AI neuroengineering and drug development company building programmable psychoactive therapeutics for mental health. Primary product is the Osmanthus platform and lead asset MSD-001, which map subjective trip-report data to receptor biology to design specific emotional and cognitive states.

Primary product

Osmanthus platform and lead asset MSD-001

Founded

2021

Headquarters

South San Francisco, California, United States

Team size

11-50

Work style

Remote

Industry

Biotechnology

Sub-industry

Clinical-stage neuroengineering / psychedelic therapeutics

Offices

South San Francisco, California, United States
Pittsburgh, Pennsylvania, United States

Business model

Drug discovery
Clinical development
Potential pharma partnering / licensing

Funding

Stage

Seed / early-stage

Total raised

$24.3M

Latest round

Undisclosed · Nov 2024

Latest amount

$12.7M

Undisclosed

Nov 2024

$12.7M

Seed

Feb 2022 · Initialized Capital

$11.5M

Pre-seed

Sep 2021 · Y Combinator

$125K

People & investors

Leadership

Dillan DiNardo

Co-Founder & CEO

Thomas Ray, PhD

Scientific Co-Founder

Robert Silva, PhD

Chief Scientific Officer

Tilmann Brotz, PhD

Head of Preclinical Development

Ken Colley, MD, PhD

Medical Director

Jianhong Wang, PhD

Head of DMPK

Jessica Smith Beaver, PhD, MLS

Head of Regulatory Affairs

Tegan Johnson

Senior Director of Operations

Jasminder Soto

Head of Clinical Operations

Antonio Socorro

Head of Drug Product & Formulation

Michael Hoyos

Head of Business Development

Graeme Bell

Independent Board Director

Investors

10X Capital
Actions Capital
Apoorva Mehta
Ayuh Ventures
Blast.club
Cursive Holdings
Day One Ventures
Empath Ventures
Fred Ehrsam
Hub Angels Investment Group
Immeasurable
Initialized Capital
Innovating Capital
K50 Ventures
Lionheart Ventures
Max Hodak
Metaplanet Holdings
Mystic Ventures
Naval Ravikant
Negev Capital
One Mind Accelerator
Page One Ventures
Rand Hindi
Y Combinator

Work & culture

Mission-driven, research-heavy, and expert-led; public materials emphasize a top-tier team, remote-first operation, and building novel therapeutics in a fast-moving clinical-stage setting.

Work style

Remote

Compensation

Public job posting describes compensation as competitive and paired with full health coverage and a remote-first setup.

Benefits

Full health insurance premiums covered
Complete tech setup for remote work
Remote-first setup
Competitive compensation

Product & market

Pricing

Not publicly disclosed; primarily drug-development and potential partnering/licensing economics.

Differentiators

  • —Osmanthus uses AI to synthesize subjective trip reports with biochemical data
  • —Focuses on designing psychoactive states rather than only single molecules
  • —Lead program aims for emotional and cognitive flexibility without hallucinations
  • —Uses a primer/probe approach to engineer specific effects
  • —Clinical-stage human studies already underway

Technology

multi-agent LLMs
large language models
natural language processing
frontier/custom embedding models
Bayesian neural networks
machine learning
biochemical data synthesis
receptor-activity mapping

Competitors

MindMed
Compass Pathways
Beckley Psytech
Alto Neuroscience
Filament Health
Helus Pharma
VCENNA
Biomind Labs

Scale & contact

Estimated revenue

about $1M annually

info@mindstate.design

Latest news

Mindstate Design Labs announces the appointment of Graeme Bell to its Board of Directors

Mindstate Design Labs · Dec 2025

Company press release announcing Graeme Bell as an independent board director; also reiterates the Osmanthus platform and provides a public contact email.

Topline study MSD-001 clinical trial results and lead fixed-dose combination program announcement

Mindstate Design Labs · Sep 2025

Official announcement of topline MSD-001 study results and the lead fixed-dose combination program.

Mindstate heads to the clinic with first AI-derived psychedelic

Fierce Biotech · Mar 2024

Reports that Mindstate submitted its first IND for MSD-001 and outlined its AI-driven approach to designing psychoactive states.

Mindstate Design Labs raised an $11.5M seed round for psychedelic-inspired therapeutics

Technical.ly · Feb 2022

Adds Pittsburgh context and confirms the seed round and company mission in psychedelic-inspired therapeutics.

Mindstate Design Labs Raised a $11.5 Million Seed Round

Business Insider · Feb 2022

Covers the $11.5M seed round led by Initialized Capital and participation from a group of venture and angel investors.

Board appointment press releaseCareers / open applicationClinical trial newsLinkedIn company pageOfficial websitePrivacy policySEC Form D indexSeed round articleX accountY Combinator profile
SourcesOfficial websiteCareers / open applicationPrivacy policyY Combinator profileLinkedIn company pageCB Insights profileCrunchbase profileSEC Form D indexBusiness Insider seed round articleFierce Biotech clinic articleTechnical.ly seed round article

Jobs and careers at Mindstate Design Labs

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