Substack · Feb 2025
Profile/article discussing Mike Polcari and Haplotype Labs’ push to bring polygenic risk insights into clinical workflows and prevention programs.
Personalized prevention using genetics and AI
Company research
Public company, workplace, funding, and market signals
Updated Jul 29, 2026
Overview
Haplotype Labs is a YC Winter 2024, founder-led SaaS startup building HaploHub, a genetics and AI platform for genetic testing labs, concierge/clinical practices, trials, and payers/providers to predict disease risk, host/manage/interrogate genetic data, and run common inference workflows. Publicly sourced pages did not surface standalone GitHub or X accounts.
Primary product
HaploHub
Founded
2024
Headquarters
Orinda, California, United States
Team size
1-10
Work style
Flexible
Industry
Software Development
Sub-industry
Genomics / population genetics SaaS
Offices
Orinda, California, United States (headquarters)
Berkeley, California, United States (job location)
San Francisco, California, United States (YC listing)
Business model
SaaS
B2B software
platform
Funding
Stage
Seed
Total raised
$1.6M
Latest round
Seed · Apr 2024
Latest amount
$1.1M
Apr 2024
Jan 2024 · Y Combinator
People & investors
Leadership
Founder & CEO
Work & culture
Mission-driven, very early-stage startup focused on precision prevention, healthspan, and making advanced genetics software easier to deploy. Small team, founder-led, YC-backed, and hiring in a remote-US / Berkeley-friendly manner.
Work style
Flexible
Compensation
YC job posting for a Founding Member(s) of Technical Staff advertised a salary range of $60K-$240K; no broader public compensation policy was found.
Product & market
Pricing
Subscription / SaaS; third-party pricing listings suggest an entry price from about $49/mo, but the company has not publicly published a formal price card.
Differentiators
- —Uses proprietary or 4,000+ publicly available genetic models
- —Runs common inference algorithms without code (phasing, imputation, IBD, etc.)
- —Securely hosts, manages, and interrogates genetic data
- —Supports any genome-wide germ-line or methylation assay
- —Claims 50%–90% sequencing cost savings via low-pass sequencing
Technology
AWS
Google Cloud
Python
Docker
Bioinformatics
Biostatistics
Genomics
Customers
genetic testing labs
concierge medical practices
clinical trials
payers/providers
consumer brands
prevention-focused medical practices
Scale & contact
Estimated revenue
$50K-$100K
Estimated monthly visits
300
Latest news
SEC · Apr 2024
Official Form D index for Haplotype Labs, Inc.; supports the seed financing disclosure and company address/phone details.
Fundz · Apr 2024
News-style funding alert echoing the $1.1M filing and describing the company’s genetics-and-AI product.
Y Combinator
Launch post describing HaploHub, the target customer segments, and founder Mike Polcari’s background; confirms YC Winter 2024 launch and product positioning.
Jobs and careers at Haplotype Labs
0 jobs at Haplotype Labs
No open positions
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