Substrate blog · Jul 2026
Introduces the public Substrate API for programmatic access to claim-status workflows, with docs, auth details, and integration guidance.
Public company, workplace, funding, and market signals
Updated Jul 29, 2026
Substrate (substrate.cc / substrateai.com) is a San Francisco-based YC S24 startup building AI agents for healthcare revenue cycle management, with products for claim status, appeals, eligibility, exception posting, and patient refunds.
Primary product
AI-native revenue cycle automation platform (Claim Status Agent and related RCM agents)
Founded
2024
Headquarters
San Francisco, California, United States
Team size
10-20
Work style
Flexible
Industry
Healthcare technology
Sub-industry
Revenue cycle management (RCM) automation / medical billing AI
Offices
7 jobs at Substrate
Business model
Stage
Pre-seed
Total raised
$500K
Latest round
Pre-Seed · Sep 2024
Latest amount
$500K
Sep 2024 · Y Combinator
Leadership
Co-founder & CEO
Founder
Founding Account Executive
Investors
Small, high-ownership team with a low-ego, no-BS culture; hiring for judgment and deep healthcare/RCM expertise; recruiting is primarily in person in San Francisco.
Work style
Flexible
Compensation
No public salary bands or compensation ranges were found; hiring materials emphasize high-impact, judgment-heavy roles rather than disclosed pay bands.
Pricing
Quote-based / demo-led; no public pricing posted.
Differentiators
Technology
Customers
Competitors
Estimated revenue
≈$330K ARR (GetLatka estimate, 2025)
Estimated monthly visits
1.3K
Traffic estimate as of Jun 2026
Substrate blog · Jul 2026
Introduces the public Substrate API for programmatic access to claim-status workflows, with docs, auth details, and integration guidance.
Business Wire · Jul 2026
Official launch note for the Eligibility Agent, which expands Substrate’s healthcare RCM automation into front-end denial prevention and eligibility workflows.
Substrate changelog · Jun 2026
Product update adding clearinghouse checks to the claim-status workflow so rejected claims can be identified and routed back to worklists.
Business Wire · Apr 2026
Press release describing the Claim Status Agent and its multi-route approach across EDI, portals, and APIs for claim monitoring.