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Epinoma

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Epinoma

We engineer proteins that control the operating system of biology.

epinoma.com
HQ: San Francisco, CA, USA
1-10
Healthcare

Company research

Public company, workplace, funding, and market signals

Updated Jul 29, 2026

Overview

Epinoma is a San Carlos-based biotechnology research / diagnostics company developing EpiAmp, a methyl-preserving, conversion-free amplification platform for DNA methylation analysis used in early cancer detection, MRD monitoring, and epigenetic therapeutics. Public funding records are inconsistent across databases, but the clearest source-backed announcement is a $3M seed financing led by SeedToB Capital.

Primary product

EpiAmp methyl-preserving amplification platform

Founded

2020

Headquarters

930 Brittan Avenue, San Carlos, CA 94070, United States

Team size

1-10

Industry

Biotechnology Research

Sub-industry

Epigenetic diagnostics

Offices

San Carlos, California, United States
Santa Clara, California, United States
San Francisco, California, United States

Business model

B2B platform licensing
Custom assay / panel development
Research tools and workflows
Diagnostics enabling technology

Funding

Stage

Seed

Total raised

$3M

Latest round

Seed · Oct 2021

Latest amount

$3M

Seed

Oct 2021 · SeedToB Capital

$3M

People & investors

Leadership

Varun Govil

CEO and Co-Founder

Ishan Goyal

Co-Founder and Chief Operating Officer

Abizar Lakdawalla

Advisor, Product Development Strategy

Founders

Zhijian Li

Co-Founder

Investors

Asymmetry Ventures
Ethan Perlstein
George Church
Jude Gomila
Katie Fifer
Ken Drobish
Mo Zohour
Murray Reicher
MyAsiaVC
Rajeev Oak
Ray Wu
SeaX Ventures
SeedToB Capital
Y Combinator

Work & culture

Public careers copy emphasizes a multi-disciplinary, mission-driven scientific team and values of boldness, excellence, integrity, and collaboration; Epinoma also states it is an equal opportunity employer.

Compensation

Public job postings on YC list a Therapeutic Research Associate at $70K-$95K with 0.10%-0.25% equity and a Protein Scientist role at $90K-$125K with 0.25%-1.00% equity; no broader compensation policy is publicly posted.

Product & market

Pricing

Not publicly disclosed; appears to be B2B platform licensing and custom assay development.

Differentiators

  • —Methylation-preserving, conversion-free amplification
  • —Higher sensitivity than bisulfite / enzymatic workflows
  • —Compatible with gDNA, cfDNA, and FFPE samples
  • —Single-day turnaround
  • —Platform-agnostic across sequencing and PCR readouts
  • —Designed for low-input / rare-sample use cases
  • —Targets cancer detection, MRD monitoring, and epigenetic medicine workflows

Technology

EpiAmp
methyl-preserving amplification
protein engineering
epigenetics / epigenome assays
gDNA
cfDNA
FFPE
qMSP
EM-seq
WGBS
PCR
NGS
single-cell workflows
TALENs
CRISPR
zinc fingers
protein-DNA interaction assays

Customers

Blood test developers
Liquid biopsy companies
Biopharma companies
Clinical researchers
Pharmaceutical R&D teams
Vesica Health (pilot customer / partner)

Competitors

Lucira Health
Gemelli Biotech
Syros Pharmaceuticals
Chroma Medicine
FOXO Technologies
Chronomics
Epsilen Bio

Scale & contact

Estimated revenue

USD 0 - 1,000,000

Estimated monthly visits

130

press@epinoma.com

Latest news

EpiAmp whitepaper announcement

LinkedIn · Oct 2025

Varun Govil announced the first EpiAmp dataset and whitepaper, claiming >99% per-doubling accuracy, faithful 5mC preservation across millions of CpG sites, and compatibility with short-read, long-read, and PCR-based workflows.

Epinoma to Commercialize Methylation-Preserving Amplification Chemistry Developed at UChicago

GenomeWeb · Sep 2025

GenomeWeb reported Epinoma is commercializing EpiAmp, an exclusive-license methylation-preserving amplification chemistry developed at the University of Chicago. The article highlights low-input performance, >99% per-cycle preservation claims, pilot studies with partners such as Vesica Health, and an early-access launch plan.

The Missing Piece: Epinoma Advances Novel Disease Detection Tech

Polsky Center · Jul 2025

The University of Chicago Polsky Center profile says Epinoma licensed the DNA methylation analysis technology, adapted it into a commercial-grade product, and is positioning EpiAmp for broader research and clinical adoption, including cancer detection and AI-enabled diagnostics.

CareersGenomeWeb coverageHomepageLinkedIn company pageNewsPolsky Center coveragePrivacy / addressPRWeb seed funding announcementTechnologyY Combinator profile
SourcesOfficial websiteTechnology pageCareers pagePrivacy pageLinkedIn company pageY Combinator company pageSeedtoB PRWeb funding announcementGenomeWeb 2025 articlePolsky Center 2025 articleLinkedIn founder financing postCrunchbase company profile

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