Business Wire · Feb 2026
Announced major enhancements to DiffuseSandbox and RamaX, enabling design of up to 10,000 sequences and screening against up to 100 antigens in parallel, with 1-2 week binder discovery turnaround.
Company research
Public company, workplace, funding, and market signals
Updated Jul 30, 2026
Overview
Diffuse Bio is a San Carlos, California biotech building generative AI and experimental platforms for protein design, with a self-serve design app and linked wet-lab screening workflow for engineering protein therapeutics, diagnostics, and enzymes.
Primary product
DiffuseSandbox, the self-serve AI protein design platform integrated with RamaX screening
Founded
2022
Headquarters
San Carlos, California, United States
Team size
10-20
Work style
Flexible
Industry
Biotechnology Research
Sub-industry
Generative AI for protein design / AI drug discovery
Offices
San Carlos, California, United States
San Francisco, California, United States
Business model
Self-serve software platform
Usage-based / quote-based screening workflow
Custom data generation and model-development partnerships
Research tooling for protein engineering
Funding
Stage
early-stage VC / seed
Total raised
$500K
Latest round
Early Stage VC · Mar 2024
Mar 2024
Sep 2023 · Fellows Fund
Jan 2023 · Y Combinator
Jan 2023 · Y Combinator
People & investors
Work & culture
Mission-driven, interdisciplinary team of scientists, machine learning researchers, and engineers focused on rapid experimentation and bridging AI research with biological reality through in-house assay development and data generation.
Work style
Flexible
Visa sponsorship
Limited
Compensation
Public job posting shows a Software Engineer salary range of $90K-$130K plus 0.05%-0.60% equity; Bay Area preferred, remote possible for exceptional candidates; US citizens or visa holders only.
Product & market
Pricing
Free-starting-credits self-serve platform with quote-based screening and partnership/custom development pricing
Differentiators
- —Combines AI design with in-house experimental validation
- —Fast binder discovery workflow targeting 1-2 week turnaround
- —No-code / low-code self-serve interface for researchers
- —Can generate up to 10,000 designs and screen against up to 100 antigens in parallel
- —Uses in-house assay development and biological data generation to improve models
- —Claims one-shot precision and strong binder performance in company research
Technology
Python
C++
SQL
Google Cloud
Google App Engine
Kubernetes
React
HTML
CSS
JavaScript
DiffuseSandbox
RamaX
RamaX Opt
DSG2-mini
DSG1
yeast display
high-throughput protein screening
Customers
Researchers worldwide
Pharma companies
Biotech companies
Teams working on therapeutics
Teams working on diagnostics
Teams working on enzyme development
Scale & contact
Estimated monthly visits
4.4K
Latest news
Business Wire · Jun 2025
Public launch of DSG2-mini in DiffuseSandbox, the first time researchers could directly access Diffuse Bio's protein design capability through the web platform.
LinkedIn · Jun 2024
Namrata Anand shared DSG-1 results showing ~3% binder hit rate, strong sub-10nM binders, and the team's progression toward a foundation model for protein design.
NBC (local syndication) · Mar 2023
Interview coverage featuring Namrata Anand discussing Diffuse Bio's mission to use AI to speed up protein and drug development.
The New York Times · Jan 2023
High-profile coverage of AI protein design that helped spotlight the broader technical area Diffuse Bio operates in.
Jobs and careers at Diffuse Bio
0 jobs at Diffuse Bio
No open positions
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