Singularity Capital · Jun 2025
Portfolio write-up summarizing the company’s disease-focused model, founders’ backgrounds, and named investors.
A Disease Focused Biotech, Building Multiple Billion Dollar Drugs
Public company, workplace, funding, and market signals
Updated Jul 29, 2026
San Francisco biotech founded in 2024 that is building multi-modal therapeutics for Rett syndrome and other rare diseases, using a lean, expert-led, capital-efficient approach that combines disease biology, AI, CROs, and existing modality tools to advance preclinical drug candidates.
Primary product
Multi-modal rare-disease therapeutics, starting with Rett syndrome candidates
Founded
2024
Headquarters
San Francisco, California, United States
Team size
1-10
Industry
Biotechnology Research
Sub-industry
Rare disease therapeutics
Offices
0 jobs at Uncommon Therapeutics
Check back later for new openings
Business model
Stage
seed
Total raised
$500K
Latest round
Seed · Feb 2025
Latest amount
$500K
Feb 2025 · Y Combinator
Investors
Mission-driven, patient-first, and highly capital-efficient; the company emphasizes deep disease expertise, rapid validation, and a small expert team working with external CROs and advisors.
Differentiators
Technology
Competitors
Estimated revenue
~$330K estimated annual revenue
Singularity Capital · Jun 2025
Portfolio write-up summarizing the company’s disease-focused model, founders’ backgrounds, and named investors.
Hiretop · Apr 2025
Editorial profile on the startup’s mission, Rett syndrome thesis, and early therapeutic candidates.
Y Combinator · Feb 2025
YC launch post highlighting the company’s rare-disease strategy, founder story, and early preclinical therapeutics in patient cell lines.
Startup Intros · Feb 2025
Product launch profile describing the company’s Rett syndrome focus, capital-efficient approach, and early preclinical progress.
Startup Intros · Feb 2025
Reports the company’s $500K seed round and names Y Combinator and Angel Operator Partners as investors.