PR Newswire / Dentistry.One · Jul 2026
Bristle announced a strategic partnership with Dentistry.One to combine oral microbiome testing with virtual oral-health coaching, teledental consultations, and nationwide care navigation.
At-home oral health testing, coaching & care
Company research
Public company, workplace, funding, and market signals
Updated Jul 30, 2026
Overview
Bristle is a San Francisco-based oral health company that provides at-home oral microbiome saliva testing, personalized insights, coaching, and probiotic products to help users identify and address the root causes of oral-health issues.
Primary product
Bristle Oral Microbiome / Oral Health Test
Founded
2020
Headquarters
San Francisco, California, United States
Team size
1-10
Industry
Health, Wellness & Fitness
Sub-industry
Oral health testing / microbiome diagnostics
Offices
San Francisco, California, United States
United States
India
Business model
Direct-to-consumer test kit sales
Provider/practitioner channel test ordering
Supplement/probiotic product sales
Funding
Stage
Seed
Total raised
$3.1M
Latest round
Seed · Jul 2022
Latest amount
$3M
Jul 2022 · Initialized Capital
Nov 2021 · GSK NEXT
Mar 2021 · Y Combinator
People & investors
Leadership
CEO & Co-Founder
Co-Founder & CSO
Co-Founder
Co-Founder
Jonathan Levine, DDS
Advisor
Mark Burhenne, DDS
Advisor
Work & culture
The company emphasizes prevention, science-backed root-cause oral care, and translating advanced genomics into practical health improvements.
Compensation
Public signals are limited; a historical hiring post referenced competitive salary, stock options, and hybrid work, but no current compensation data was found.
Benefits
HSA/FSA eligibility
Personalized care plans
1:1 coaching from hygienists
Product & market
Pricing
Primarily one-time paid test kits, with add-on probiotic products and practitioner ordering channel distribution.
Differentiators
- —Claims to be the first at-home oral microbiome saliva test
- —Analyzes bacteria, fungi, and viruses from a single saliva sample
- —Uses shotgun metagenomic sequencing
- —Provides personalized recommendations and care plans
- —Combines testing with coaching and preventive oral-care guidance
Technology
Shotgun metagenomic sequencing
NGS / next-generation sequencing
Saliva sample analysis
HIPAA-compliant infrastructure
Customers
Consumers
Patients with oral health concerns
Healthcare practitioners
Dental providers
Competitors
Oral Genome
Viome
Dentognostics
Prebiomics
Incisive
CefMed
Pearlii
Dental.com
DentaMitra
Scale & contact
Estimated revenue
Unknown; a third-party estimate cited $8.3M ARR, but this is not publicly confirmed by Bristle.
Latest news
Bristle blog · Jul 2024
Bristle announced a partnership with Rupa Health to make its oral microbiome test available to practitioners through the Rupa platform.
Bristle blog · Jul 2024
Bristle explained how it researches and validates the hygiene and lifestyle recommendations it gives to users, and provided a contact email for questions.
Bristle blog · Oct 2022
Bristle announced a $3M seed round led by Initialized Capital with participation from Y Combinator and Anne Wojcicki.
Jobs and careers at Bristle
0 jobs at Bristle
No open positions
Check back later for new openings