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Blank Bio

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Blank Bio

RNA-based AI for better drugs and smarter clinical trials.

blank.bio
HQ: San Francisco, CA, USA
1-10
Healthcare

Company research

Public company, workplace, funding, and market signals

Updated Jul 29, 2026

Overview

Blank Bio is a San Francisco-based YC S25 applied AI research lab building RNA foundation models for precision oncology and clinical-trial decision support. It was founded in 2025, raised a $7.2M seed round in May 2026, and is collaborating with PacBio on long-read RNA-seq data to improve patient-level prediction.

Primary product

RNA foundation models for precision oncology and clinical-trial decision support (including its bulk transcriptomics model Ladon)

Founded

2025

Headquarters

San Francisco, California, United States

Team size

2-10 employees

Industry

Biotechnology Research

Sub-industry

RNA foundation models / precision oncology AI

Offices

San Francisco, California, United States

Business model

B2B enterprise platform
research partnerships with pharma and diagnostics
clinical trial decision-support software

Funding

Stage

Seed

Total raised

$7.2M

Latest round

Seed · May 2026

Latest amount

$7.2M

Seed

May 2026

$7.2M

People & investors

Leadership

Jonathan Hsu

Co-Founder & CEO

Philip Fradkin

Co-Founder

Ruian Shi

Co-Founder

Investors

Define Ventures
Leonis Capital
Nova Threshold
Ripple Ventures
SignalFire
Y Combinator

Work & culture

Early-stage, fast-moving, cross-disciplinary, and comfortable with ambiguity; the team emphasizes ownership and helping shape both the science and the culture.

Visa sponsorship

Yes

Compensation

Public job postings show salaries of roughly $125K-$250K depending on role, plus 0.20%-1.00% early-stage equity.

Benefits

Competitive salary
Meaningful early-stage equity
Health coverage
Dental coverage
Vision coverage
Generous vacation
Parental leave
Visa sponsorship available

Product & market

Pricing

Custom enterprise / research-partnership pricing; not publicly disclosed.

Differentiators

  • —Trains RNA foundation models on bulk RNA-seq and transcriptomic data
  • —Focuses on patient heterogeneity for trial design and response prediction
  • —Uses clinically accessible bulk RNA-seq as the core signal
  • —Collaborates with PacBio for long-read, isoform-resolution RNA data
  • —Open-source models reportedly used by Sanofi and GSK
  • —Builds embedding-search tools for scientific discovery
  • —Published benchmarking work such as mRNABench

Technology

Python
Docker
container orchestration
RNA-seq data pipelines
bulk transcriptomics foundation models
embedding-search MCP
benchmarking suites
Claude Science integration

Customers

Pharmaceutical companies
Biotech companies
Diagnostic companies
mRNA therapeutics companies
CRISPR therapeutics companies
RNA biomarker teams

Competitors

Evotec
Strand Life Sciences
DNAnexus
other RNA / precision-medicine AI platforms

Scale & contact

founders@blank.bio

Latest news

AI agents will accelerate scientific discovery when grounded in biological data

Blank Bio · Jul 2026

Blank Bio introduced Ladon, its bulk transcriptomics foundation model, and described its embedding-search MCP for scientific discovery.

Blank Bio Announces Seed Financing and Strategic Collaboration with PacBio to Advance RNA Foundation Models for Precision Oncology

Business Wire · May 2026

Blank Bio announced a $7.2M seed round and a strategic collaboration with PacBio to generate long-read RNA-seq data for model training and evaluation.

Blank Bio Raises $7.2M in Seed Funding for RNA Foundation Model Development

GenomeWeb · May 2026

GenomeWeb covered the seed round, investors, and the PacBio collaboration, including the company’s use of public and proprietary RNA-seq data.

Blank Bio Announces Seed Financing and Strategic Collaboration with PacBio to Advance RNA Foundation Models for Precision Oncology

BioSpace · May 2026

BioSpace republished the press release describing the seed financing, founders, and collaboration details.

BlogCareersGitHub repo referenced in blogLinkedIn company pageOfficial websiteSeed announcementSubstackWriting / latest technical postX accountYC company page
SourcesOfficial websiteYC company pageYC jobs pageBioSpace press releaseBusinessWire press releaseGenomeWeb articleLinkedIn company pageCompany blogLatest blog postSubstack post

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