AbbVie announced a definitive agreement to acquire bretisilocin for up to $1.2 billion, including upfront payment and milestones, and Gilgamesh planned to spin out the remaining company and programs.
SourceGilgamesh Pharmaceuticals, a Clinical stage biotechnology company…
Public company, workplace, funding, and market signals
Gilgamesh Pharmaceuticals is a New York-based clinical-stage neuroscience biotech founded in 2019 that develops novel chemical entities for psychiatric disease, with a focus on rapid-acting, durable therapies. Its current lead program is blixeprodil (GM-1020), an oral NMDA receptor antagonist for major depressive disorder; its earlier lead, bretisilocin, was acquired by AbbVie in 2025.
Primary product
Blixeprodil (GM-1020)
Founded
2019
Headquarters
New York, New York, United States
Team size
20-30
Work style
Flexible
Industry
Pharmaceutical Manufacturing
Sub-industry
Clinical-stage neuroscience biotech
Offices
0 jobs at Gilgamesh Pharmaceuticals
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Business model
Stage
Series A
Total raised
$149.5M
Latest round
Series A · Mar 2026
Latest amount
$60M
Leadership
Founder, CEO
Co-Founder, CSO
Chief Strategy & Development Officer
Chief Medical Officer
Chief Business Officer & Head of Research
Chief Operating Officer
EVP of Biology and Translational Medicine
Investors
Mission-driven, science-heavy, and compact; public messaging emphasizes experienced drug-development leadership, rapid-acting and durable psychiatric therapies, and partnership-oriented execution.
Work style
Flexible
Compensation
No public salary bands were found. Hiring posts indicate senior US-based, fully remote roles; one CMC - Drug Substance posting asked for a PhD and 5-10+ years of experience.
Pricing
Not publicly disclosed; appears to be a B2B biopharma partnering/licensing model.
Differentiators
Competitors
Estimated revenue
approximately $6M (public estimates range $1M-$10M)
Estimated monthly visits
12.9K
Traffic estimate as of Jul 2026
AbbVie announced a definitive agreement to acquire bretisilocin for up to $1.2 billion, including upfront payment and milestones, and Gilgamesh planned to spin out the remaining company and programs.
SourceAbbVie completed its acquisition of Gilgamesh Pharmaceuticals' bretisilocin, leaving the remaining programs and employees in the spun-out Gilgamesh Pharma entity.
SourcePRNewswire · Mar 2026
Announced a $60M Series A led by Satori Neuro; described the spinout company and its lead program blixeprodil.
PRNewswire · Jan 2026
Reported positive Phase 2a data for the oral NMDA receptor antagonist blixeprodil, including durable antidepressant effects.
AbbVie · Oct 2025
AbbVie completed its acquisition of bretisilocin, expanding its psychiatry pipeline.
AbbVie · Aug 2025
Definitive agreement for AbbVie to acquire bretisilocin for up to $1.2B and spin out the remaining Gilgamesh business.
PRNewswire · May 2025
Reported positive Phase 2a data for GM-2505/bretisilocin, including high remission rates and durable efficacy.