BioAge discontinued the STRIDES Phase 2 obesity trial of azelaprag after transaminitis/liver-enzyme elevations were observed in some participants; dosing stopped and the company said it would reassess the program.
SourceClinical-stage biotech developing therapies for aging.
Public company, workplace, funding, and market signals
Updated Jul 29, 2026
Clinical-stage biopharmaceutical company using longitudinal human-aging data and multi-omics to develop therapies for metabolic disease; lead asset BGE-102 is an oral, brain-penetrant NLRP3 inhibitor for cardiovascular risk and retinal disease. Public GitHub not found.
Primary product
BGE-102, an orally available, brain-penetrant small-molecule NLRP3 inhibitor
Founded
2015
Headquarters
Emeryville, California, United States
Team size
51-200
Work style
Remote
Industry
Biotechnology Research
Sub-industry
Clinical-stage cardiometabolic therapeutics
Offices
1 job at BioAge Labs
Business model
Stage
Public
Total raised
$624.2M
Latest round
Follow-on public offering · Feb 2026
Latest amount
$132.3M
Feb 2026
Sep 2024
Feb 2024 · Sofinnova Investments
Dec 2020 · Andreessen Horowitz and Elad Gil
Jan 2019 · Felicis Ventures
Jul 2017 · Andreessen Horowitz Bio Fund
Leadership
Co-Founder, CEO
Co-Founder, COO
CMO & EVP, Research
Chief Financial Officer
Chief Business Officer & Therapeutic Area Head, Brain Aging
Chief Development Officer
Chief Strategy Officer
Investors
Mission-driven, science-heavy, and flexible; careers page describes a remote-first culture focused on aging biology and metabolic disease discovery.
Work style
Remote
Compensation
No public salary bands found; public compensation signals are limited to a benefits-and-stipends package rather than disclosed pay ranges.
Benefits
Pricing
No public pricing; monetization appears to come from therapeutic development, collaboration revenue, licensing, and eventual drug commercialization.
Differentiators
Technology
Customers
Competitors
Estimated revenue
$1M-$10M
Estimated monthly visits
9.5K
BioAge discontinued the STRIDES Phase 2 obesity trial of azelaprag after transaminitis/liver-enzyme elevations were observed in some participants; dosing stopped and the company said it would reassess the program.
SourceBioAge terminated development of azelaprag and shifted focus to next-generation APJ and NLRP3 programs after the STRIDES discontinuation.
SourceA securities class action was filed after the IPO alleging BioAge’s offering materials failed to adequately disclose risks around the azelaprag/STRIDES trial safety profile.
SourceBioAge Labs · Jun 2026
First participant dosed in QUELL-CV, a randomized, placebo-controlled Phase 2 proof-of-concept trial of BGE-102 for elevated cardiovascular risk; topline data anticipated H2 2026.
BioAge Labs · May 2026
Reported positive April 2026 Phase 1 data for BGE-102 and outlined plans to start Phase 2 cardiovascular-risk and DME trials in mid-2026.
BioAge Labs · Apr 2026
BGE-102 showed potential best-in-class hsCRP reductions and a favorable tolerability profile in Phase 1.
BioAge Labs · Jan 2026
Priced an upsized public offering for approximately $115.0 million gross proceeds, later increased with full overallotment exercise.
Reuters · Dec 2024
Company discontinued the STRIDES Phase 2 azelaprag trial after liver-enzyme elevations were observed in some participants.