About eGenesis
eGenesis is a clinical-stage biotechnology company developing human-compatible engineered organs to address the severe global organ shortage. The Company’s proprietary genome engineering platform enables extensive, multiplex gene edits to remove key biological barriers, add protective human transgenes, and inactivate endogenous retroviruses. EGEN-2784, a genetically engineered porcine kidney, is the Company’s lead program and is currently being evaluated in a multi-patient Expanded Access study at MGH. eGenesis is headquartered in Cambridge, MA.
At eGenesis, our core values—innovation, collaboration, compassion, resilience, and passion—are at the center of how we work. We engineer hope and bring passion to everything we do. We collaborate and learn from one another, combining diverse expertise to tackle complex challenges. We innovate boldly, pushing boundaries and science to new heights. where no pig organ has gone before. With resilience, we navigate challenges and celebrate progress together. And in all we do, we lead with compassion—for our patients, our people, and our pigs.
POSITION SUMMARY The veterinary services team supports the health, welfare, and regulatory compliance of swine herds housed in the Designated Pathogen Free (DPF) and Source Animal Facility (SAF) at eGenesis. The team ensures standardized veterinary medical care, surgical excellence, herd health management, regulatory compliance, and adherence to GMP requirements. The Associate Veterinarian reports to the Director of Veterinary Services and serves primarily a clinical role in the SAF and participates frequently in the broader programs for animal health including adventitious agents surveillance, vaccine and sentinel programs. In this role, you will provide clinical and regulatory support for GMP donor production, surgical support for GMP donor production, and participate in Institutional Animal Care and Use Committee and USDA inspections. The Associate Veterinarian participates in the weekly veterinarian on-call schedule. The Associate Veterinarian serves as back up to the ART Veterinarian and Director of Veterinary Services when necessary, in roles for which they will be cross trained.Provide direct clinical and surgical care
Execute surveillance programs (SAF & DPF)
Review pathogen results and contribute to Herd Health Reports
Serve as IACUC member and USDA inspection contact
Support vaccine program selection and implementation
Participate in sentinel optimization strategy
Provide backup coverage for Director and ART Veterinarian
Participate in weekly on-call rotation
Engage in program communications and review and support ongoing collaboration with Quality and Operations teams.
Participate in monthly in-person veterinary team meetings
Contribute to semi-annual review of SOPs and program documents
Train in program surgical procedures to provide redundancy in surgical capability across the team
Maintain surgical expectations by executing standardized procedures and scheduling, owning maintenance of surgical suite readiness, and participating in ongoing surgical training and CE
Implement medical therapies and heard health program and execute standardized medication use across barns, maintain compliance with GMP and Quality-approved medication lists, participate in annual review of drug treatment spreadsheets, assist with development of standardized primary/secondary/tertiary treatment protocols, consistently document using SOAP format, and adhere to standardized euthanasia endpoint criteria (in coordination with IACUC)
Manage surveillance programs through execution of health sampling for surveillance program, ante-mortem, post-mortem and ad-hoc and review of pathogen detection results and herd health synthesis reporting
Engage in selection and ordering of vaccines in alignment with the company’s vaccine program
Actively participate in preparation and execution of organ procurement and be available on-call during enrollment/procurement periods.
Support organ procurement program through ultrasound qualification of donor pigs and completion of GMP quality documentation.
Support regulatory compliance with IACUC participation, provide USDA inspection readiness and representation, SOP authorship and change control participation, and author Quality-driven documentation and impact assessments.
Support imaging needs and perform ultrasound procedures for DS/DP animals, perform surrogate pregnancy detection (DPF), train through CE and supervised practice, complete documentation for donor qualification
DVM or VMD from AVMA-accredited institution; may substitute completion of ECFVG program for graduates of non-AVMA schools
1-3 years experience as clinical veterinarian working with large animals, preferably swine
License to practice veterinary medicine in at least one state; must attain Indiana licensure within 6 months of hire
DEA Registration for maintenance of controlled drugs on site
USDA Accreditation Category II
Working knowledge of regulatory compliance and GMP guidelines
Must be willing to accept significant learning challenges inherent in a first-in-class biotechnology startup
Excellent organizational and time management skills and the ability to prioritize work, with attention to detail and resolve to approach problems as an opportunity
Excellent verbal and written communication skills
Interpersonal skills necessary to manage others
ACLAM board certification or residency training in laboratory animal medicine with eligibility to take ACLAM board exam
Background in either swine management/research or experience in breeding/neonate management of any species. Significant swine medicine experience desired.
1-3 years of management experience
PHYSICAL DEMANDS
While performing the duties of this position, the employee is regularly required to talk or hear. The employee frequently is required to sit, stand, walk, reach with hands or arms, lift, and operate a computer. Specific vision abilities required by this position include close vision, distance vision, color vision, peripheral vision, depth perception and ability to adjust to focus. The employee frequently is required to lift laboratory supplies and equipment within the daily routine. The employee will be required to handle and work with large animals on a daily basis.
WORK ENVIRONMENT
This position will be required to shower-in into the animal facility to perform the required tasks. This position operates in multiple environments, including office, laboratory, and animal husbandry environment. This role routinely uses standard office equipment such as computers, phones, copy machines, filing cabinets, and fax machines.
POSITION SUMMARY The veterinary services team supports the health, welfare, and regulatory compliance of swine herds housed in the Designated Pathogen Free (DPF) and Source Animal Facility (SAF) at eGenesis. The team ensures standardized veterinary medical care, surgical excellence, herd health management, regulatory compliance, and adherence to GMP requirements. The Associate Veterinarian reports to the Director of Veterinary Services and serves primarily a clinical role in the SAF and participates frequently in the broader programs for animal health including adventitious agents surveillance, vaccine and sentinel programs. In this role, you will provide clinical and regulatory support for GMP donor production, surgical support for GMP donor production, and participate in Institutional Animal Care and Use Committee and USDA inspections. The Associate Veterinarian participates in the weekly veterinarian on-call schedule. The Associate Veterinarian serves as back up to the ART Veterinarian and Director of Veterinary Services when necessary, in roles for which they will be cross trained.